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Transforming Growth Factor β(1) Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts
Transforming growth factor-beta (TGF-β), a key mediator of cardiac fibroblast activation, has a major influence on collagen type I production. However, the epigenetic mechanisms by which TGF-β induces collagen type I alpha 1 (COL1A1) expression are not fully understood. This study was designed to ex...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613378/ https://ncbi.nlm.nih.gov/pubmed/23560091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060335 |
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