Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-β-stimulated collagen production by cardiac fibroblasts

AIMS: Following injury, fibroblasts transform into myofibroblasts and produce extracellular matrix (ECM). Excess production of ECM associated with cardiac fibrosis severely inhibits cardiac function. Sphingosine-1-phosphate (S1P), a bioactive lysophospholipid, regulates the function of numerous cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gellings Lowe, Nicole, Swaney, James S., Moreno, Kelli M., Sabbadini, Roger A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675932/
https://ncbi.nlm.nih.gov/pubmed/19228708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp056
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