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Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib

1. Vascular endothelial growth factor inhibitors (VEGFi) are known to cause hypertension and renal injury that severely limits their use as an anticancer therapy. We hypothesized that the angiotensin-converting enzyme inhibitor captopril not only prevents hypertension, but also decreases renal injur...

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Autors principals: Nagasawa, Tasuku, Khan, Abdul Hye, Imig, John D
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613249/
https://ncbi.nlm.nih.gov/pubmed/22443474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1681.2012.05699.x
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