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Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib

1. Vascular endothelial growth factor inhibitors (VEGFi) are known to cause hypertension and renal injury that severely limits their use as an anticancer therapy. We hypothesized that the angiotensin-converting enzyme inhibitor captopril not only prevents hypertension, but also decreases renal injur...

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Detalhes bibliográficos
Main Authors: Nagasawa, Tasuku, Khan, Abdul Hye, Imig, John D
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613249/
https://ncbi.nlm.nih.gov/pubmed/22443474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1681.2012.05699.x
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