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The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension

Soluble epoxide hydrolase inhibitors (sEHIs) are demonstrating promise as potential pharmaceutical agents for the treatment of cardiovascular disease, diabetes, inflammation, and kidney disease. The present study determined the ability of a first-in-class sEHI, AR9281, to decrease blood pressure, im...

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Bibliographic Details
Main Authors: Imig, John D., Carpenter, Margaret A., Shaw, Sean
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978544/
https://ncbi.nlm.nih.gov/pubmed/27713235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph2030217
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