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Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats

We hypothesized that perinatal inhibition of soluble epoxide hydrolase (SEH), which metabolizes epoxyeicosatrienoic acids in the arachidonic acid (AA) cascade, with an orally active SEH inhibitor, 12-(3-adamantan-1-yl-ureido)-dodecanoic acid (AUDA), would persistently reduce blood pressure (BP) in a...

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Bibliografiset tiedot
Päätekijät: Koeners, Maarten P., Wesseling, Sebastiaan, Ulu, Arzu, Sepúlveda, Rocío López, Morisseau, Christophe, Braam, Branko, Hammock, Bruce D., Joles, Jaap A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074945/
https://ncbi.nlm.nih.gov/pubmed/21266668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00710.2010
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