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P53 and p21(Waf1) are recruited to distinct PML-containing nuclear foci in irradiated and Nutlin-3a-treated U2OS cells
Promyelocytic leukemia nuclear bodies (PML-NBs) are multi-protein complexes that include PML protein and localize in nuclear foci. PML-NBs are implicated in multiple stress responses, including apoptosis, DNA repair, and p53-dependent growth inhibition. ALT-associated PML bodies (APBs) are specializ...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613244/ https://ncbi.nlm.nih.gov/pubmed/20803550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22852 |
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