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Double-strand gap repair in a mammalian gene targeting reaction.
To better understand the mechanism of homologous recombination in mammalian cells that facilitates gene targeting, we have analyzed the recombination reaction that inserts a plasmid into a homologous chromosomal locus in mouse embryonic stem cells. A partially deleted HPRT gene was targeted with var...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1875928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.9.4389 |
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