Llwytho...

Mechanism and Specificity of an Acyltransferase Domain from a Modular Polyketide Synthase

Acyltransferase (AT) domains of modular polyketide synthases exercise tight control over the choice of α-carboxyacyl-CoA substrates, but the mechanistic basis for this specificity is unknown. We show that whereas the specificity for the electrophilic malonyl or methylmalonyl component is primarily e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dunn, Briana J., Cane, David E., Khosla, Chaitan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612939/
https://ncbi.nlm.nih.gov/pubmed/23452124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400185v
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