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Isolation and Analysis of a Baculovirus Vector That Supports Recombinant Glycoprotein Sialylation by SfSWT-1 Cells Cultured in Serum-Free Medium

The inability to sialylate recombinant glycoproteins is a critical limitation of the baculovirus-insect cell expression system. This limitation is due, at least in part, to the absence of detectable sialyltransferase activities and CMP-sialic acids in the insect cell lines routinely used as hosts in...

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Main Authors: Hill, Daniel R., Aumiller, Jared J., Shi, Xianzong, Jarvis, Donald L.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612899/
https://ncbi.nlm.nih.gov/pubmed/16607656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.20945
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