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A novel baculovirus vector for the production of nonfucosylated recombinant glycoproteins in insect cells
Glycosylation is an important attribute of baculovirus-insect cell expression systems, but some insect cell lines produce core α1,3-fucosylated N-glycans, which are highly immunogenic and render recombinant glycoproteins unsuitable for human use. To address this problem, we exploited a bacterial enz...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919471/ https://ncbi.nlm.nih.gov/pubmed/24362443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwt161 |
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