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Isolation and Analysis of a Baculovirus Vector That Supports Recombinant Glycoprotein Sialylation by SfSWT-1 Cells Cultured in Serum-Free Medium
The inability to sialylate recombinant glycoproteins is a critical limitation of the baculovirus-insect cell expression system. This limitation is due, at least in part, to the absence of detectable sialyltransferase activities and CMP-sialic acids in the insect cell lines routinely used as hosts in...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612899/ https://ncbi.nlm.nih.gov/pubmed/16607656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.20945 |
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