Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers

AIM: The present study evaluated the possibility of drug interactions involving blueberry juice (BBJ) and substrate drugs whose clearance is dependent on cytochromes P4503A (CYP3A) and P4502C9 (CYP2C9). METHODS: A 50:50 mixture of lowbush and highbush BBJ was evaluated in vitro as an inhibitor of CY...

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Autores principales: Hanley, Michael J, Masse, Gina, Harmatz, Jerold S, Cancalon, Paul F, Dolnikowski, Gregory G, Court, Michael H, Greenblatt, David J
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2013
Materias:
Drug Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612722/
https://ncbi.nlm.nih.gov/pubmed/22943633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04450.x
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