Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers

AIMS: Turmeric extract derived curcuminoids (curcumin, demethoxycurcumin and bisdemethoxycurcumin) are currently being evaluated for the treatment of cancer and Alzheimer's dementia. Previous in vitro studies indicate that curcuminoids and piperine (a black pepper derivative that enhances curcu...

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Detalhes bibliográficos
Main Authors: Volak, Laurie P, Hanley, Michael J, Masse, Gina, Hazarika, Suwagmani, Harmatz, Jerold S, Badmaev, Vladimir, Majeed, Muhammed, Greenblatt, David J, Court, Michael H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579260/
https://ncbi.nlm.nih.gov/pubmed/22725836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04364.x
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