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Library of synthetic transcriptional AND gates built with split T7 RNA polymerase mutants

The construction of synthetic gene circuits relies on our ability to engineer regulatory architectures that are orthogonal to the host’s native regulatory pathways. However, as synthetic gene circuits become larger and more complicated, we are limited by the small number of parts, especially transcr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shis, David L., Bennett, Matthew R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612686/
https://ncbi.nlm.nih.gov/pubmed/23479654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220157110
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