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Library of synthetic transcriptional AND gates built with split T7 RNA polymerase mutants
The construction of synthetic gene circuits relies on our ability to engineer regulatory architectures that are orthogonal to the host’s native regulatory pathways. However, as synthetic gene circuits become larger and more complicated, we are limited by the small number of parts, especially transcr...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612686/ https://ncbi.nlm.nih.gov/pubmed/23479654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220157110 |
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