Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

Lignende værker

• Improving virtual screening of G protein-coupled receptors via ligand-directed modeling
  af: Coudrat, Thomas, et al.
  Udgivet: (2017)
• Stimulus Bias Provides Evidence for Conformational Constraints in the Structure of a G Protein-coupled Receptor
  af: Gregory, Karen J., et al.
  Udgivet: (2012)
• Consequences of splice variation on Secretin family G protein-coupled receptor function
  af: Furness, Sebastian GB, et al.
  Udgivet: (2012)
• Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor
  af: Wootten, Denise, et al.
  Udgivet: (2016)
• Structural features embedded in G protein-coupled receptor co-crystal structures are key to their success in virtual screening.
  af: Thomas Coudrat, et al.
  Udgivet: (2017-01-01)