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Mutant methionyl-tRNA synthetase from bacteria enables site-selective N-terminal labeling of proteins expressed in mammalian cells

Newly synthesized cellular proteins can be tagged with a variety of metabolic labels that distinguish them from preexisting proteins and allow them to be identified and tracked. Many such labels are incorporated into proteins via the endogenous cellular machinery and can be used in numerous cell typ...

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Detalhes bibliográficos
Main Authors: Ngo, John T., Schuman, Erin M., Tirrell, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612679/
https://ncbi.nlm.nih.gov/pubmed/23479642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216375110
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