Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains

Drosophila melanogaster Polo kinase physically interacts with, and is repressed by, the Matrimony (Mtrm) protein during oogenesis. Females heterozygous for a deletion of the mtrm gene display defects in chromosome segregation at meiosis I. However, a complete absence of Mtrm results in both meiotic...

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Bibliografski detalji
Glavni autori: Bonner, Amanda M., Hughes, Stacie E., Chisholm, Jennifer A., Smith, S. Kendall, Slaughter, Brian D., Unruh, Jay R., Collins, Kimberly A., Friederichs, Jennifer M., Florens, Laurence, Swanson, Selene K., Pelot, Marissa C., Miller, Danny E., Washburn, Michael P., Jaspersen, Sue L., Hawley, R. Scott
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612667/
https://ncbi.nlm.nih.gov/pubmed/23479640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301690110
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