Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains

Drosophila melanogaster Polo kinase physically interacts with, and is repressed by, the Matrimony (Mtrm) protein during oogenesis. Females heterozygous for a deletion of the mtrm gene display defects in chromosome segregation at meiosis I. However, a complete absence of Mtrm results in both meiotic...

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Detalhes bibliográficos
Main Authors: Bonner, Amanda M., Hughes, Stacie E., Chisholm, Jennifer A., Smith, S. Kendall, Slaughter, Brian D., Unruh, Jay R., Collins, Kimberly A., Friederichs, Jennifer M., Florens, Laurence, Swanson, Selene K., Pelot, Marissa C., Miller, Danny E., Washburn, Michael P., Jaspersen, Sue L., Hawley, R. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612667/
https://ncbi.nlm.nih.gov/pubmed/23479640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301690110
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