Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis

Cancer metastasis and immune suppression are critical issues in cancer therapy. Here, we show that a β-galactoside–binding lectin [galectin-3 (gal3)] that recognizes the Thomsen-Friedenreich disaccharide (TFD, Galβ1,3GalNAc) present on the surface of most cancer cells is involved in promoting angiog...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Guha, Prasun, Kaptan, Engin, Bandyopadhyaya, Gargi, Kaczanowska, Sabina, Davila, Eduardo, Thompson, Keyata, Martin, Stuart S., Kalvakolanu, Dhananjaya V., Vasta, Gerardo R., Ahmed, Hafiz
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612646/
https://ncbi.nlm.nih.gov/pubmed/23479624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202653110
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars