B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells

Although innate immune responses are necessary for the initiation of acquired immune responses and the subsequent successful elimination of pathogens, excessive responses occasionally result in lethal endotoxic shock accompanied by a cytokine storm. B and T lymphocyte attenuator (BTLA), a coinhibito...

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Bibliografski detalji
Glavni autori: Kobayashi, Yoshihisa, Iwata, Arifumi, Suzuki, Kotaro, Suto, Akira, Kawashima, Saki, Saito, Yukari, Owada, Takayoshi, Kobayashi, Midori, Watanabe, Norihiko, Nakajima, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612598/
https://ncbi.nlm.nih.gov/pubmed/23479601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222093110
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