B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells

Although innate immune responses are necessary for the initiation of acquired immune responses and the subsequent successful elimination of pathogens, excessive responses occasionally result in lethal endotoxic shock accompanied by a cytokine storm. B and T lymphocyte attenuator (BTLA), a coinhibito...

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Detalhes bibliográficos
Main Authors: Kobayashi, Yoshihisa, Iwata, Arifumi, Suzuki, Kotaro, Suto, Akira, Kawashima, Saki, Saito, Yukari, Owada, Takayoshi, Kobayashi, Midori, Watanabe, Norihiko, Nakajima, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612598/
https://ncbi.nlm.nih.gov/pubmed/23479601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222093110
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