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Hypoxia Inducible Factor-1α (HIF-1α) and Some HIF-1 Target Genes are Elevated in Experimental Glaucoma

Low levels of hypoxia have been suggested to be a mechanism of retinal damage in glaucoma. To test the hypothesis that the activation of the hypoxia-responsive transcription factor hypoxia inducible factor-1α (HIF-1α) is involved in the pathophysiology of glaucoma, we used a rat model of glaucoma to...

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Autors principals: Ergorul, Ceren, Ray, Arjun, Huang, Wei, Wang, Dan Yi, Ben, Yixin, Cantuti-Castelvetri, Ippolita, Grosskreutz, Cynthia L.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612432/
https://ncbi.nlm.nih.gov/pubmed/20237864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-010-9343-z
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