RNA Interference of GADD153 Protects Photoreceptors from Endoplasmic Reticulum Stress-Mediated Apoptosis after Retinal Detachment

BACKGROUND: Apoptosis of photoreceptors plays a critical role in the vision loss caused by retinal detachment (RD). Pharmacologic inhibition of photoreceptor cell death may prevent RD. This study investigated the role of GADD153 that participates in endoplasmic reticulum (ER) stress-mediated apoptos...

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Detalhes bibliográficos
Main Authors: Zhu, Hong, Qian, Jin, Wang, Wenqiu, Yan, Quan, Xu, Ying, Jiang, Yuan, Zhang, Lei, Lu, Fengqing, Hu, Weiting, Zhang, Xi, Wang, Fenghua, Sun, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612068/
https://ncbi.nlm.nih.gov/pubmed/23555658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059339
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