RNA Interference of GADD153 Protects Photoreceptors from Endoplasmic Reticulum Stress-Mediated Apoptosis after Retinal Detachment

BACKGROUND: Apoptosis of photoreceptors plays a critical role in the vision loss caused by retinal detachment (RD). Pharmacologic inhibition of photoreceptor cell death may prevent RD. This study investigated the role of GADD153 that participates in endoplasmic reticulum (ER) stress-mediated apoptos...

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Main Authors: Zhu, Hong, Qian, Jin, Wang, Wenqiu, Yan, Quan, Xu, Ying, Jiang, Yuan, Zhang, Lei, Lu, Fengqing, Hu, Weiting, Zhang, Xi, Wang, Fenghua, Sun, Xiaodong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612068/
https://ncbi.nlm.nih.gov/pubmed/23555658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059339
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