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Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA.

The translation of human triosephosphate isomerase (TPI) mRNA normally terminates at codon 249 within exon 7, the final exon. Frameshift and nonsense mutations within the TPI gene that cause translation to terminate prematurely at or upstream of codon 189, within exon 6, result in a decreased level...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Cheng, J, Fogel-Petrovic, M, Maquat, L E
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1990
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2398889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.10.5215
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