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Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice.

Recent studies have demonstrated that transcriptional activation of the human adult beta-globin transgene in mice by coinsertion of the beta-globin cluster locus control region (beta-LCR) results in loss of its adult restricted pattern of expression. Normal developmental control is reestablished by...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Albitar, M, Katsumata, M, Liebhaber, S A
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361149/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1710771/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.7.3786-3794.1991
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