Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice.
Recent studies have demonstrated that transcriptional activation of the human adult beta-globin transgene in mice by coinsertion of the beta-globin cluster locus control region (beta-LCR) results in loss of its adult restricted pattern of expression. Normal developmental control is reestablished by...
Shranjeno v:
| izdano v: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1991
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1710771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.7.3786-3794.1991 |
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