LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell models

Mutations in the genes encoding leucine-rich repeat kinase 2 (LRRK2) and α-synuclein are associated with both autosomal dominant and idiopathic forms of Parkinson’s disease (PD). α-Synuclein is the main protein in Lewy bodies, hallmark inclusions present in both sporadic and familial PD. We show tha...

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Main Authors: Guerreiro, Patrícia Silva, Huang, Yue, Gysbers, Amanda, Cheng, Danni, Gai, Wei Ping, Outeiro, Tiago Fleming, Halliday, Glenda Margaret
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611031/
https://ncbi.nlm.nih.gov/pubmed/23183827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0984-y
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