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Neuronatin-mediated Aberrant Calcium Signaling and Endoplasmic Reticulum Stress Underlie Neuropathology in Lafora Disease

Lafora disease (LD) is a teenage-onset inherited progressive myoclonus epilepsy characterized by the accumulations of intracellular inclusions called Lafora bodies and caused by mutations in protein phosphatase laforin or ubiquitin ligase malin. But how the loss of function of either laforin or mali...

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Detalhes bibliográficos
Main Authors: Sharma, Jaiprakash, Mukherjee, Diptendu, Rao, Sudheendra N. R., Iyengar, Soumya, Shankar, Susarla Krishna, Satishchandra, Parthasarathy, Jana, Nihar Ranjan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611017/
https://ncbi.nlm.nih.gov/pubmed/23408434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416180
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