Leucine Facilitates Insulin Signaling through a Gα(i) Protein-dependent Signaling Pathway in Hepatocytes

In this study, we addressed the direct effect of leucine on insulin signaling. In investigating the associated mechanisms, we found that leucine itself does not activate the classical Akt- or ERK1/2 MAP kinase-dependent signaling pathways but can facilitate the insulin-induced phosphorylations of Ak...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yang, Xuefeng, Mei, Shuang, Wang, Xiaolei, Li, Xiang, Liu, Rui, Ma, Yan, Hao, Liping, Yao, Ping, Liu, Liegang, Sun, Xiufa, Gu, Haihua, Liu, Zhenqi, Cao, Wenhong
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2013
Θέματα:
Metabolism
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611002/
https://ncbi.nlm.nih.gov/pubmed/23404499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409409
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