Reversing the Warburg Effect as a Treatment for Glioblastoma

Glioblastoma multiforme (GBM), like most cancers, possesses a unique bioenergetic state of aerobic glycolysis known as the Warburg effect. Here, we documented that methylene blue (MB) reverses the Warburg effect evidenced by the increasing of oxygen consumption and reduction of lactate production in...

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Detalhes bibliográficos
Main Authors: Poteet, Ethan, Choudhury, Gourav Roy, Winters, Ali, Li, Wenjun, Ryou, Myoung-Gwi, Liu, Ran, Tang, Lin, Ghorpade, Anuja, Wen, Yi, Yuan, Fang, Keir, Stephen T., Yan, Hai, Bigner, Darell D., Simpkins, James W., Yang, Shao-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610988/
https://ncbi.nlm.nih.gov/pubmed/23408428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440354
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