2,2′-Diphenyl-3,3′-Diindolylmethane: A Potent Compound Induces Apoptosis in Breast Cancer Cells by Inhibiting EGFR Pathway

Despite recent advances in medicine, 30–40% of patients with breast cancer show recurrence underscoring the need for improved effective therapy. In this study, by in vitro screening we have selected a novel synthetic indole derivative 2,2'-diphenyl-3,3'-diindolylmethane (DPDIM) as a potent...

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Main Authors: Bhowmik, Arijit, Das, Nilanjana, Pal, Uttam, Mandal, Madhumita, Bhattacharya, Seemana, Sarkar, Moumita, Jaisankar, Parasuraman, Maiti, Nakul C., Ghosh, Mrinal K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610887/
https://ncbi.nlm.nih.gov/pubmed/23555785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059798
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