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Targeted Deletion of the Metastasis-Associated Phosphatase Ptp4a3 (PRL-3) Suppresses Murine Colon Cancer

Ptp4a3 (commonly known as PRL-3) is an enigmatic member of the Ptp4a family of prenylated protein tyrosine phosphatases that are highly expressed in many human cancers. Despite strong correlations with tumor metastasis and poor patient prognosis, there is very limited understanding of this gene fami...

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Detalhes bibliográficos
Main Authors: Zimmerman, Mark W., Homanics, Gregg E., Lazo, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610886/
https://ncbi.nlm.nih.gov/pubmed/23555575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058300
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