The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia

BACKGROUND: Resistance to tyrosine kinase inhibitors (TKIs) remains a challenge in management of patients with chronic myeloid leukemia (CML). A better understanding of the BCR-ABL signalling network may lead to better therapy. FINDINGS: Here we report the discovery of a novel downstream target of B...

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Detalhes bibliográficos
Main Authors: Zhou, Jianbiao, Cheong, Lip-Lee, Liu, Shaw-Cheng, Chong, Phyllis SY, Mahara, Sylvia, Bi, Chonglei, Ong, Kelly OK, Zeng, Qi, Chng, Wee Joo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537646/
https://ncbi.nlm.nih.gov/pubmed/22995644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-72
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