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Phosphatase PRL-3 is a Direct Regulatory Target of TGFβ in Colon Cancer Metastasis

Metastasis causes most deaths from cancer yet mechanistic understanding and therapeutic options remain limited. Overexpression of the phosphatase PRL-3 is associated with metastasis of colon cancer. Here we show here that PRL-3 is a direct target of signaling by transforming growth factor β (TGFβ),...

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Detalhes bibliográficos
Main Authors: Jiang, Yanjun, Liu, Xiao-Qiong, Rajput, Ashwani, Geng, Liying, Ongchin, Melanie, Zeng, Qi, Taylor, Gregory S., Wang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064433/
https://ncbi.nlm.nih.gov/pubmed/21084277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1487
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