Restoration of Transforming Growth Factor-β Receptor II Expression in Colon Cancer Cells with Microsatellite Instability Increases Metastatic Potential in Vivo

Microsatellite instability (MSI), which occurs in 15% of colorectal cancer, has been shown to have a lower incidence of metastasis and better patient survival rates compared with microsatellite stable colorectal cancer. However, a mechanistic understanding of the basis for this difference is very li...

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Autores principales: Liu, Xiao-Qiong, Rajput, Ashwani, Geng, Liying, Ongchin, Melanie, Chaudhuri, Anathbandhu, Wang, Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091217/
https://ncbi.nlm.nih.gov/pubmed/21454688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221697
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