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polyQ disease: misfiring of a developmental cell death program?
Polyglutamine-repeat diseases are neurodegenerative ailments elicited by glutamine-encoding CAG nucleotide expansions within endogenous human genes. Despite efforts to understand the basis of these diseases, the precise mechanism of cell death remains stubbornly unclear. Much of the data seems consi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610856/ https://ncbi.nlm.nih.gov/pubmed/23228508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2012.11.003 |
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