A single amino acid change in CUP2 alters its mode of DNA binding.
CUP2 is a copper-dependent transcriptional activator of the yeast CUP1 metallothionein gene. In the presence of Cu+ and Ag+) ions its DNA-binding domain is thought to fold as a cysteine-coordinated Cu cluster which recognizes the palindromic CUP1 upstream activation sequence (UASc). Using mobility s...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
1990
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2167439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4778-4787.1990 |
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