A single amino acid change in CUP2 alters its mode of DNA binding.

CUP2 is a copper-dependent transcriptional activator of the yeast CUP1 metallothionein gene. In the presence of Cu+ and Ag+) ions its DNA-binding domain is thought to fold as a cysteine-coordinated Cu cluster which recognizes the palindromic CUP1 upstream activation sequence (UASc). Using mobility s...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Buchman, C, Skroch, P, Dixon, W, Tullius, T D, Karin, M
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1990
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2167439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4778-4787.1990
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