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Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung
Pneumococcal carriage is both immunising and a pre-requisite for mucosal and systemic disease. Murine models of pneumococcal colonisation show that IL-17A-secreting CD4(+) T-cells (Th-17 cells) are essential for clearance of pneumococci from the nasopharynx. Pneumococcal-responding IL-17A-secreting...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610738/ https://ncbi.nlm.nih.gov/pubmed/23555269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003274 |
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