Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults

Rationale: The immunological and protective role of pneumococcal carriage in healthy adults is not known, but high rates of disease and death in the elderly are associated with low carriage prevalence. Objectives: We employed an experimental human pneumococcal carriage model to investigate the immun...

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Detalhes bibliográficos
Main Authors: Ferreira, Daniela M., Neill, Daniel R., Bangert, Mathieu, Gritzfeld, Jenna F., Green, Nicola, Wright, Adam K. A., Pennington, Shaun H., Moreno, Laura Bricio, Moreno, Adriana T., Miyaji, Eliane N., Wright, Angela D., Collins, Andrea M., Goldblatt, David, Kadioglu, Aras, Gordon, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707375/
https://ncbi.nlm.nih.gov/pubmed/23370916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201212-2277OC
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