Human Nasal Challenge with Streptococcus pneumoniae Is Immunising in the Absence of Carriage

Infectious challenge of the human nasal mucosa elicits immune responses that determine the fate of the host-bacterial interaction; leading either to clearance, colonisation and/or disease. Persistent antigenic exposure from pneumococcal colonisation can induce both humoral and cellular defences that...

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Detalhes bibliográficos
Main Authors: Wright, Adam K. A., Ferreira, Daniela M., Gritzfeld, Jenna F., Wright, Angela D., Armitage, Kathryn, Jambo, Kondwani C., Bate, Emily, El Batrawy, Sherouk, Collins, Andrea, Gordon, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320601/
https://ncbi.nlm.nih.gov/pubmed/22496648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002622
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