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DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in Vertebrates
Biochemical and genetic studies suggest that vertebrates remove double-strand breaks (DSBs) from their genomes predominantly by two non-homologous end joining (NHEJ) pathways. While canonical NHEJ depends on the well characterized activities of DNA-dependent protein kinase (DNA-PK) and LIG4/XRCC4/XL...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610672/ https://ncbi.nlm.nih.gov/pubmed/23555685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059505 |
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