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Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells
In eukaryotes, the three families of ATP-dependent DNA ligases are associated with specific functions in DNA metabolism. DNA ligase I (LigI) catalyzes Okazaki-fragment ligation at the replication fork and nucleotide excision repair (NER). DNA ligase IV (LigIV) mediates repair of DNA double strand br...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315315/ https://ncbi.nlm.nih.gov/pubmed/22127868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1024 |
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