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The Tolerogenic Peptide, hCDR1, Down-Regulates the Expression of Interferon-α in Murine and Human Systemic Lupus Erythematosus

BACKGROUND: The tolerogenic peptide, hCDR1, ameliorated manifestations of systemic lupus erythematosus (SLE) via the immunomodulation of pro-inflammatory and immunosuppressive cytokines and the induction of regulatory T cells. Because type I interferon (IFN-α) has been implicated to play a role in S...

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Detalhes bibliográficos
Main Authors: Sthoeger, Zev, Zinger, Heidy, Sharabi, Amir, Asher, Ilan, Mozes, Edna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610660/
https://ncbi.nlm.nih.gov/pubmed/23555966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060394
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