A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4(+)CD25(+) cells and TGF-β

Systemic lupus erythematosus is an autoimmune disease characterized by autoantibodies and systemic clinical manifestations. A peptide, designated hCDR1, based on the complementarity-determining region (CDR) 1 of an autoantibody, ameliorated the serological and clinical manifestations of lupus in bot...

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Hlavní autoři: Sharabi, Amir, Zinger, Heidy, Zborowsky, Maya, Sthoeger, Zev M., Mozes, Edna
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482660/
https://ncbi.nlm.nih.gov/pubmed/16735466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603201103
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