Amelioration of lupus manifestations by a peptide based on the complementarity determining region 1 of an autoantibody in severe combined immunodeficient (SCID) mice engrafted with peripheral blood lymphocytes of systemic lupus erythematosus (SLE) patients

A peptide based on the complementarity determining region (CDR)1 of a human monoclonal anti-DNA autoantibody (hCDR1) was shown to either prevent or treat an already established murine lupus in systemic lupus erythematosus (SLE)-prone mice or in mice with induced experimental SLE. The present study w...

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Main Authors: MAUERMANN, N, STHOEGER, Z, ZINGER, H, MOZES, E
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2004
Assuntos:
Animal Studies
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809128/
https://ncbi.nlm.nih.gov/pubmed/15320900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02559.x
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