A tolerogenic peptide down-regulates mature B cells in bone marrow of lupus-afflicted mice by inhibition of interleukin-7, leading to apoptosis

Systemic lupus erythematosus (SLE) is an autoimmune disease mediated by T and B cells. It is characterized by a variety of autoantibodies and systemic clinical manifestations. A tolerogenic peptide, designated hCDR1, ameliorated the serological and clinical manifestations of SLE in both spontaneous...

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Main Authors: Ben-David, Hava, Sharabi, Amir, Parameswaran, Reshmi, Zinger, Heidy, Mozes, Edna
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2009
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767314/
https://ncbi.nlm.nih.gov/pubmed/19740381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03109.x
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